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A mutation in the tbxt gene, involving a unique dna insertion, caused tail loss in humans and great apes 20 million years ago. Genetically modified mice with the short tbxt protein developed no tails or shorter tails, mimicking human evolution. Scientists now know why human ancestors lost their tails 25 million years ago and its down to a single snippet of dna, a new study revealed.
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The researchers discovered the genetic change. Around 25 million years ago, this parasite, a small stretch of repetitive dna called an alu element, ended up in a gene important for tail development, researchers report in the feb. A genetic change in our ancient ancestors may partly explain why humans dont have tails like monkeys, finds a new study led by researchers at nyu grossman school of medicine. Published online february 28 as the cover story of the journal nature, the work compared the dna of tailless apes and humans to that of tailed monkeys.
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Having a tail separates monkeys from apes like us. A team of geneticists, affiliated with nyu langone health in new york city, published a new paper in the journal nature. Their research suggests that a seemingly random piece of dna inserted into the genome of a human ancestor is responsible for the loss of the tail in modern humans and apes. Understanding the genetics of tail loss in hominoids may provide insight into the evolutionary pressure that led to human traits such as bipedalism.