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Depending on the dice roll on the floor there is different effects. If you're having an amazing run and find a dice room that you don't know the effet of, i'd be careful, it may shuffle you to worse items. If you want a damage item then mom's knife is the best standalone damage item for pure damage output, though epic fetus is also great and effectively gives you infinite bombs as a bonus.
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I found a dice room that changed all my crappy items(really crappy) and got lord of the flies + orbital stationary tears of fear/charm that was also piercing and spectral and gigantic. I went to sheol and finished satan in 2 seconds. Which type of dice room you like the most? The 5 because there's no downside to it.
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I think d6 is the best for those who dare to play bad runs without holding r key down. 4 and 5 are by far the best ones but i guess room 4 since that one is always nice. Sometimes i don't need room 5. Dice rooms are special rooms that can randomize many elements of the run. Dice rooms require two keys to be opened, unlike most other special rooms.
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